Activation of androgen receptor-associated protein 70 (ARA70) mRNA expression in ovarian cancer.

@article{Shaw2001ActivationOA,
  title={Activation of androgen receptor-associated protein 70 (ARA70) mRNA expression in ovarian cancer.},
  author={Patricia A. Shaw and Paula V.C. Rittenberg and Theodore J Brown},
  journal={Gynecologic oncology},
  year={2001},
  volume={80 2},
  pages={132-8}
}
OBJECTIVE Androgens have been implicated in ovarian cancer and androgen receptor expression has been reported in 70-95% of ovarian adenocarcinomas, implying a role in ovarian cancer cell biology. Androgen receptor-associated protein 70 (ARA70) is a reported androgen receptor coactivator that enhances the transactivational potential of the androgen receptor up to 10-fold. Because ARA70 expression could amplify androgen action in ovarian cancer cells, we examined patient samples of ovarian cancer… CONTINUE READING

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