Activation of alpha1D adrenergic receptors in the rat urothelium facilitates the micturition reflex.

@article{Ishihama2006ActivationOA,
  title={Activation of alpha1D adrenergic receptors in the rat urothelium facilitates the micturition reflex.},
  author={H. Ishihama and Y. Momota and H. Yanase and X. Wang and W. D. de Groat and M. Kawatani},
  journal={The Journal of urology},
  year={2006},
  volume={175 1},
  pages={
          358-64
        }
}
  • H. Ishihama, Y. Momota, +3 authors M. Kawatani
  • Published 2006
  • Medicine
  • The Journal of urology
  • PURPOSE Previous studies have revealed that the activation of alpha(1) adrenergic receptors in urothelial cells releases neurotransmitters. We determined if alpha(1D) adrenergic receptors are expressed in the urothelium of the rat bladder and if inhibition of these receptors affects reflex voiding. MATERIALS AND METHODS Female Wistar rats were used in the experiments. Receptor expression was evaluated by Western blot. The effects of receptor activation were studied using cystometrograms… CONTINUE READING
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