Activation of afferent renal nerves modulates RVLM-projecting PVN neurons.

  title={Activation of afferent renal nerves modulates RVLM-projecting PVN neurons.},
  author={Bo Xu and Hong Helena Zheng and Xuefei Liu and Kaushik P. Patel},
  journal={American journal of physiology. Heart and circulatory physiology},
  volume={308 9},
Renal denervation for the treatment of hypertension has proven to be successful; however, the underlying mechanism/s are not entirely clear. To determine if preautonomic neurons in the paraventricular nucleus (PVN) respond to afferent renal nerve (ARN) stimulation, extracellular single-unit recording was used to investigate the contribution of the rostral ventrolateral medulla (RVLM)-projecting PVN (PVN-RVLM) neurons to the response elicited during stimulation of ARN. In 109 spontaneously… CONTINUE READING
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