Activation of adenylyl cyclase in Chlamydomonas reinhardtii by adhesion and by heat

@article{Saito1993ActivationOA,
  title={Activation of adenylyl cyclase in Chlamydomonas reinhardtii by adhesion and by heat},
  author={Takako Saito and Linda Small and Ursula W. Goodenough},
  journal={The Journal of Cell Biology},
  year={1993},
  volume={122},
  pages={137 - 147}
}
Adhesion between Chlamydomonas reinhardtii gametes generates a rapid rise in cAMP levels which stimulates mating responses and zygotic cell fusion (Pasquale and Goodenough, 1987). We show here that sexual adhesion in vivo results in a twofold stimulation of flagellar adenylyl cyclase activity when the enzyme is subsequently assayed in vitro, a stimulation that is specifically blocked by Cd2+. A twofold stimulation is also elicited by the in vitro presentation of soluble cross-linking reagents… CONTINUE READING

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