Activation of Wnt/β-Catenin Pathway in Monocytes Derived from Chronic Kidney Disease Patients

@inproceedings{AlChaqmaqchi2013ActivationOW,
  title={Activation of Wnt/β-Catenin Pathway in Monocytes Derived from Chronic Kidney Disease Patients},
  author={Heevy Abdulkareem Musa Al-Chaqmaqchi and Ali Moshfegh and Elham Dadfar and Josefin M. Paulsson and Moustapha Hassan and Stefan H. Jacobson and J. U. E. Lundahl},
  booktitle={PloS one},
  year={2013}
}
Patients with chronic kidney disease (CKD) have significantly increased morbidity and mortality resulting from infections and cardiovascular diseases. Since monocytes play an essential role in host immunity, this study was directed to explore the gene expression profile in order to identify differences in activated pathways in monocytes relevant to the pathophysiology of atherosclerosis and increased susceptibility to infections. Monocytes from CKD patients (stages 4 and 5, estimated GFR <20 ml… CONTINUE READING