Activation of Toll-like receptors inhibits herpes simplex virus-1 infection of human neuronal cells.

Abstract

Toll-like receptors (TLRs) play an essential role in initiating intracellular type I interferon (IFN)-mediated innate immunity against viral infections. We examined whether human neuronal cells (primary human neurons, NT2-N and CHP-212 cells) express TLRs and mount type I IFN-mediated innate immunity against herpes simplex virus-1 (HSV-1) infection. Human… (More)
DOI: 10.1002/jnr.22110

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@article{Zhou2009ActivationOT, title={Activation of Toll-like receptors inhibits herpes simplex virus-1 infection of human neuronal cells.}, author={Yu Zhou and Li Ye and Qi Wan and Lin Zhou and Xu Wang and Jieliang Li and Shuxian Hu and Dunjin Zhou and Wen-zhe Ho}, journal={Journal of neuroscience research}, year={2009}, volume={87 13}, pages={2916-25} }