Activation of Si-Si Bonds for Copper(I)-Catalyzed Conjugate Silylation.


Several alkyl- and vinylsilanes were prepared through the copper(I)-catalyzed conjugate silylation of α,β-unsaturated compounds. Optimal reaction conditions were first investigated to realize the conjugate addition of a nucleophilic silicon species to poorly electrophilic acceptors such as phenylvinyl sulfone by cleavage of the Si-Si bond of a disilane reagent. The scope of this reaction was extended to various electrophiles bearing different electron-withdrawing groups and afforded the desired substituted alkyl- and vinylsilanes. Among the wide range of commercially available disilanes, the reactivities of alkyl-, aryl-, and ethoxydisilane were also examined.

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@article{Iannazzo2012ActivationOS, title={Activation of Si-Si Bonds for Copper(I)-Catalyzed Conjugate Silylation.}, author={Laura Iannazzo and Gary A Molander}, journal={European journal of organic chemistry}, year={2012}, volume={2012 26}, pages={4923-4926} }