Activation of RegIIIβ/γ and interferon γ expression in the intestinal tract of SCID mice: an innate response to bacterial colonisation of the gut

@inproceedings{Keilbaugh2005ActivationOR,
  title={Activation of RegIIIβ/γ and interferon γ expression in the intestinal tract of SCID mice: an innate response to bacterial colonisation of the gut},
  author={Sue A. Keilbaugh and Marcus E. Shin and Romain Banchereau and Laila D. McVay and N. Boyko and David Artis and John J. Cebra and Gary D. Wu},
  year={2005}
}
Background and aims: The mechanisms by which commensal bacteria provoke intestinal inflammation in animal models of inflammatory bowel disease (IBD) remain incompletely defined, leading to increasing interest in the innate immune response of the colonic mucosa to bacterial colonisation. Methods: Using gene expression profiling of colonic RNA from C.B17.SCID germ free mice and those colonised with altered Schaedler’s flora, we investigated the innate immune response to bacterial colonisation… CONTINUE READING

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