Activation of Peroxisome Proliferator-Activated Receptor-Gamma by Glitazones Reduces the Expression and Release of Monocyte Chemoattractant Protein-1 in Human Mesothelial Cells

@inproceedings{Sauter2012ActivationOP,
  title={Activation of Peroxisome Proliferator-Activated Receptor-Gamma by Glitazones Reduces the Expression and Release of Monocyte Chemoattractant Protein-1 in Human Mesothelial Cells},
  author={Matthias Sauter and Kathrin Kastenm{\"u}ller and Franziska Belling and Markus Woernle and Roland Ladurner and Thomas Mussack and Thomas Sitter},
  booktitle={Mediators of inflammation},
  year={2012}
}
Human peritoneal mesothelial cells (MC) play an important role in inflammatory processes of the peritoneal cavity by producing various cytokines and chemokines, such as monocyte chemoattractant protein-1 (MCP-1). The present study was designed to assess the effect of the peroxisome proliferator-activated receptor-gamma- (PPARγ-) activator rosiglitazone on the mesothelial MCP-1 expression and release. Primary cultures of MC were obtained from omental tissue. MCP-1 antigen concentrations were… CONTINUE READING

Similar Papers

References

Publications referenced by this paper.
SHOWING 1-10 OF 27 REFERENCES

ACE inhibitor and AT1-receptor blocker attenuate the production of VEGF in mesothelial cells.

  • Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
  • 2007
VIEW 1 EXCERPT

Rosiglitazone reduces insulin requirement and C-reactive protein levels in type 2 diabetic patients receiving peritoneal dialysis.

  • American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2005
VIEW 1 EXCERPT