Activation of MAPK signaling pathway is essential for Id-1 induced serum independent prostate cancer cell growth

Abstract

The helix–loop–helix protein Id-1 has been suggested to play a positive role in cell proliferation and tumorigenesis of many types of human cancers. However, little is known about the molecular mechanism involved in the function of Id-1. In this study, using four stable Id-1 transfectant clones, we investigated the involvement of MAPK signaling pathway in… (More)
DOI: 10.1038/sj.onc.1206007

Topics

5 Figures and Tables