Activation of JNK pathway in persistent pain.

  title={Activation of JNK pathway in persistent pain.},
  author={Yong-Jing Gao and R M Ji},
  journal={Neuroscience letters},
  volume={437 3},
The c-Jun N-terminal kinase (JNK) is a stress-activated member of MAP kinase family. JNK activation has been strongly implicated in inflammatory responses, neurodegeneration, and apoptosis. Recent evidence shows that JNK pathway is also transiently activated in primary sensory neurons after tissue or nerve injury, which is required for the development of… CONTINUE READING