Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease

@inproceedings{Friesen2017ActivationOI,
  title={Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease},
  author={Max Friesen and Raymond Camahort and Youn-Kyoung Lee and Fang Xia and Robert E. Gerszten and Eugene P. Rhee and Rahul C. Deo and Chad A. Cowan},
  booktitle={Stem cell reports},
  year={2017}
}
The striking rise of obesity-related metabolic disorders has focused attention on adipocytes as critical mediators of disease phenotypes. To better understand the role played by excess adipose in metabolic dysfunction it is crucial to decipher the transcriptional underpinnings of the low-grade adipose inflammation characteristic of diseases such as type 2… CONTINUE READING