Activation of GATA4 gene expression at the early stage of cardiac specification

@inproceedings{Yilbas2014ActivationOG,
  title={Activation of GATA4 gene expression at the early stage of cardiac specification},
  author={Ayse E. Yilbas and Alison B Hamilton and Yingjian Wang and Hymn Mach and Natascha Lacroix and Darryl R Davis and Jihong Chen and Qiao Li},
  booktitle={Front. Chem.},
  year={2014}
}

• Ayse E. Yilbas, Alison B Hamilton, +5 authors Qiao Li
• Published 2014 in Front. Chem.
• DOI:10.3389/fchem.2014.00012

Currently, there are no effective treatments to directly repair damaged heart tissue after cardiac injury since existing therapies focus on rescuing or preserving reversibly damaged tissue. Cell-based therapies using cardiomyocytes generated from stem cells present a promising therapeutic approach to directly replace damaged myocardium with new healthy tissue. However, the molecular mechanisms underlying the commitment of stem cells into cardiomyocytes are not fully understood and will be… CONTINUE READING

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