Activation of ERK2 by respiratory syncytial virus in A549 cells is linked to the production of interleukin 8.

@article{Chen2000ActivationOE,
  title={Activation of ERK2 by respiratory syncytial virus in A549 cells is linked to the production of interleukin 8.},
  author={Weizu Chen and Martha M. Monick and Aaron Brent Carter and Gary W. Hunninghake},
  journal={Experimental lung research},
  year={2000},
  volume={26 1},
  pages={
          13-26
        }
}
The airway inflammation that results from respiratory syncytial virus infection is associated with a marked increase in interleukin 8 and neutrophils in the infected sites of the lung. In this study, the relationship between production of interleukin 8, infection of A549 cells by the virus, and activation of mitogen-activated protein kinases (MAPKs) was investigated. Infection of A549 cells by the virus caused an increase on the activity of extracellular signal-regulated kinase 2 (ERK2) by… CONTINUE READING

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