Activation of Delta Opioid Receptors Induces Receptor Insertion and Neuropeptide Secretion


Here we describe a novel mechanism for plasma membrane insertion of the delta opioid receptor (DOR). In small dorsal root ganglion neurons, only low levels of DORs are present on the cell surface, in contrast to high levels of intracellular DORs mainly associated with vesicles containing calcitonin gene-related peptide (CGRP). Activation of surface DORs… (More)
DOI: 10.1016/S0896-6273(02)01103-0


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