Activation of D1, but not D2 Receptors Potentiates Dizocilpine-Mediated Disruption of Prepulse Inhibition of the Startle

@article{Bortolato2005ActivationOD,
  title={Activation of D1, but not D2 Receptors Potentiates Dizocilpine-Mediated Disruption of Prepulse Inhibition of the Startle},
  author={Marco Bortolato and Gian Nicola Aru and Mauro F{\`a} and Roberto Frau and Marco Orr{\'u} and Paola Salis and Alberto Casti and Grant Christopher Luckey and Giampaolo Mereu and Gian Luigi Gessa},
  journal={Neuropsychopharmacology},
  year={2005},
  volume={30},
  pages={561-574}
}
Although substantial evidence has shown interactions between glutamatergic and dopaminergic systems play a cardinal role in the regulation of attentional processes, their involvement in informational filtering has been poorly investigated. Chiefly, little research has focused on functional correlations between the dopaminergic system and the mechanism of action of N-methyl-D-aspartate (NMDA) receptor antagonists on sensorimotor gating. The present study was targeted at evaluating whether the… CONTINUE READING

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