Activation of Broca's area during the production of spoken and signed language: a combined cytoarchitectonic mapping and PET analysis.

@article{Horwitz2003ActivationOB,
  title={Activation of Broca's area during the production of spoken and signed language: a combined cytoarchitectonic mapping and PET analysis.},
  author={Barry Horwitz and Katrin Amunts and Rajan Bhattacharyya and Debra J Patkin and Keith Jeffries and Karl Zilles and Allen R. Braun},
  journal={Neuropsychologia},
  year={2003},
  volume={41 14},
  pages={1868-76}
}
Broca's area in the inferior frontal gyrus consists of two cytoarchitectonically defined regions-Brodmann areas (BA) 44 and 45. Combining probabilistic maps of these two areas with functional neuroimaging data obtained using PET, it is shown that BA45, not BA44, is activated by both speech and signing during the production of language narratives in bilingual subjects fluent from early childhood in both American Sign Language (ASL) and English when the generation of complex movements and sounds… CONTINUE READING
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