Activation of AP5-sensitive NMDA Receptors is Not Required to Induce LTP of Synaptic Transmission in the Lateral Perforant Path.

@article{Bramham1991ActivationOA,
  title={Activation of AP5-sensitive NMDA Receptors is Not Required to Induce LTP of Synaptic Transmission in the Lateral Perforant Path.},
  author={Clive R Bramham and Norton W. Milgram and Bolek Srebro},
  journal={The European journal of neuroscience},
  year={1991},
  volume={3 12},
  pages={
          1300-1308
        }
}
The role of the N-methyl-d-aspartate (NMDA) type of glutamate receptor in long-term potentiation (LTP) of the medial (MPP) and lateral (LPP) divisions of the perforant path - granule cell system was investigated in urethane-anaesthetized rats. A stimulating electrode was positioned in the dorsomedial or ventrolateral aspect of the angular bundle for selective activation of either the MPP or LPP, respectively. A push - pull cannula served to focally perfuse artificial cerebrospinal fluid (ACSF… CONTINUE READING
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