Activation of 5-HT2B Receptors in the Medial Amygdala causes Anxiolysis in the Social Interaction Test in the Rat

@article{Duxon1997ActivationO5,
  title={Activation of 5-HT2B Receptors in the Medial Amygdala causes Anxiolysis in the Social Interaction Test in the Rat},
  author={Mark S. Duxon and Guy A. Kennett and Sean Lightowler and Thomas P Blackburn and Kevin C.F. Fone},
  journal={Neuropharmacology},
  year={1997},
  volume={36},
  pages={601-608}
}

The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats

Probably reflecting its distinctive ability to selectively and preferentially activate pre- versus postsynaptic 5-HT1A receptors, S15535 suppresses hippocampal 5- HT release and displays marked anxiolytic-like effects over a broad dose range in the relative absence of motor perturbation.

Differential roles of amygdaloid nuclei in the anxiolytic- and antidepressant-like effects of the V1b receptor antagonist, SSR149415, in rats

While the antidepressant- like effects of SSR149415 are mediated by different amygdaloid nuclei, its anxiolytic-like effects appear to involve only the basolateral nucleus of the amygdala, adding further evidence to the role of extrahypothalamic vasopressinergic systems in the control of emotional responses.

Effects of selective serotonin2 ligands on behaviors evoked by stress in the rat

Neuronal localization of the 5-HT2 receptor family in the amygdaloid complex

The present review reports data concerning the distribution and the functional roles of the 5-HT2 receptor family in the amygdalar microcircuits, which could play a critical role in the formation of emotional memories.

m-CPP-induced self-grooming is mediated by 5-HT2C receptors

Effects of centrally administered anxiolytic compounds in animal models of anxiety

...

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