Activation-induced cytidine deaminase splicing patterns in chronic lymphocytic leukemia.


Activation-induced cytidine deaminase (AID) is critically implicated in somatic hypermutation (SHM) and class switch recombination (CSR). AID is expressed as a native transcript and as several splice variants, with as yet undefined roles. Chronic lymphocytic leukemia (CLL) leukemic B cells have also been shown to express AID transcripts, especially in cases… (More)
DOI: 10.1016/j.bcmd.2009.12.005


4 Figures and Tables