Activation in dorsolateral prefrontal cortex in response to maternal criticism and praise in recovered depressed and healthy control participants

@article{Hooley2005ActivationID,
  title={Activation in dorsolateral prefrontal cortex in response to maternal criticism and praise in recovered depressed and healthy control participants},
  author={Jill M Hooley and Staci A Gruber and Laurie A. Scott and Jordan B. Hiller and Deborah A. Yurgelun-Todd},
  journal={Biological Psychiatry},
  year={2005},
  volume={57},
  pages={809-812}
}
BACKGROUND High family levels of expressed emotion reliably predict relapse in patients with schizophrenia and mood disorders; however, the neural mechanisms linking expressed emotion and relapse are unexplored. Dysfunctional activity in the dorsolateral prefrontal cortex (DLPFC) has been implicated in the pathophysiology of depression. Functional magnetic resonance imaging (fMRI) was used to assess focal activation changes in DLPFC in response to a novel psychosocial challenge stimulus… CONTINUE READING
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