Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated.

@article{Suryawan2007ActivationBI,
  title={Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated.},
  author={Agus Suryawan and Ren{\'a}n A. Orellana and Hanh V. Nguyen and Asumthia S Jeyapalan and Jillian R Fleming and Teresa A Davis},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2007},
  volume={293 6},
  pages={E1597-605}
}
Insulin and amino acids act independently to stimulate protein synthesis in skeletal muscle of neonatal pigs, and the responses decrease with development. The purpose of this study was to compare the separate effects of fed levels of INS and AA on the activation of signaling components leading to translation initiation and how these responses change with development. Overnight-fasted 6- (n = 4/group) and 26-day-old (n = 6/ group) pigs were studied during 1) euinsulinemic… CONTINUE READING

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