Activation by caecal reduction of the azo dye D & C red no. 9 to a bacterial mutagen.

@article{Dillon1994ActivationBC,
  title={Activation by caecal reduction of the azo dye D & C red no. 9 to a bacterial mutagen.},
  author={Drupadi Dillon and Robert Combes and Errol Zeiger},
  journal={Mutagenesis},
  year={1994},
  volume={9 4},
  pages={295-9}
}
D & C Red No. 9 is a monoazo dye used for manufacturing printing inks, rubber and plastics, and as an additive in cosmetics and drugs. In an NTP carcinogenicity study in rats and mice it induced splenic sarcomas and liver nodules in male rats; no chemical-related tumours were induced in mice. On the basis of its contradictory responses in a range of in vitro tests and its inactivity in several in vivo genotoxicity assays, it has been suggested that the dye may act as a non-genotoxic carcinogen… CONTINUE READING