Activation by SLAM Family Receptors Contributes to NK Cell Mediated “Missing-Self” Recognition

Abstract

Natural Killer (NK) cells attack normal hematopoietic cells that do not express inhibitory MHC class I (MHC-I) molecules, but the ligands that activate NK cells remain incompletely defined. Here we show that the expression of the Signaling Lymphocyte Activation Molecule (SLAM) family members CD48 and Ly9 (CD229) by MHC-I-deficient tumor cells significantly… (More)
DOI: 10.1371/journal.pone.0153236

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Cite this paper

@inproceedings{AlariPahissa2016ActivationBS, title={Activation by SLAM Family Receptors Contributes to NK Cell Mediated “Missing-Self” Recognition}, author={Elisenda Alari-Pahissa and Camille Grandcl{\'e}ment and Beena Patricia Jeevan-Raj and Georges Leclercq and Andr{\'e} Veillette and Werner Held}, booktitle={PloS one}, year={2016} }