Activation by KRN2391 and nicorandil of glibenclamide-sensitive K+ channels in Xenopus oocytes.

Abstract

KRN2391 (N-cyano-N'-(2-nitroxyethyl)-3-pyridine-carboximidamide methanesulfonate) and nicorandil, a new class of K+ channel openers, each with an NO2 moiety, induced outward K+ currents in follicle-enclosed Xenopus oocytes. These K+ currents were suppressed concentration-dependently and reversibly by glibenclamide, phentolamine and trifluoperazine, all… (More)

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@article{Sakuta1993ActivationBK, title={Activation by KRN2391 and nicorandil of glibenclamide-sensitive K+ channels in Xenopus oocytes.}, author={Hiraki Sakuta and K. Okamoto}, journal={European journal of pharmacology}, year={1993}, volume={244 3}, pages={277-83} }