Activation by Attention of the Human Reticular Formation and Thalamic Intralaminar Nuclei

  title={Activation by Attention of the Human Reticular Formation and Thalamic Intralaminar Nuclei},
  author={Shigeo Kinomura and Jonas Larsson and Bal{\'a}zs Guly{\'a}s and Per E. Roland},
  pages={512 - 515}
It has been known for over 45 years that electrical stimulation of the midbrain reticular formation and of the thalamic intralaminar nuclei of the brain alerts animals. However, lesions of these sectors fail to impair arousal and vigilance in some cases, making the role of the ascending activating reticular system controversial. Here, a positron emission tomographic study showed activation of the midbrain reticular formation and of thalamic intralaminar nuclei when human participants went from… 

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Discharge rate and excitability of cortically projecting intralaminar thalamic neurons during waking and sleep states

  • L. GlennM. Steriade
  • Biology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1982
The features of cortically projecting intralaminar neurons that relay MRF activity fit in well with their hypothesized role in the tonic activation processes that characterize both W and D states as compared to S sleep, and several lines of evidence suggest that sustained hyperpolarization prevails in intralamar neurons during S sleep.