Activation and shedding of platelet glycoprotein IIb/IIIa under non-physiological shear stress

@article{Chen2015ActivationAS,
  title={Activation and shedding of platelet glycoprotein IIb/IIIa under non-physiological shear stress},
  author={Zengsheng Chen and Nandan Kumar Mondal and Jun Ding and Steven C. Koenig and Mark S. Slaughter and Bartley P. Griffith and Zhongjun J Wu},
  journal={Molecular and Cellular Biochemistry},
  year={2015},
  volume={409},
  pages={93-101}
}
The purpose of this study was to investigate the influence of non-physiological high shear stress on activation and shedding of platelet GP IIb/IIIa receptors. The healthy donor blood was exposed to three levels of high shear stresses (25, 75, 125 Pa) from the physiological to non-physiological status with three short exposure time (0.05, 0.5, 1.5 s… CONTINUE READING