Activation and modulation of recombinantly expressed serotonin receptor type 3A by terpenes and pungent substances.


Serotonin receptor type 3 (5-HT3 receptor) is a ligand-gated ion channel that is expressed in the central nervous system (CNS) as well as in the peripheral nervous system (PNS). The receptor plays an important role in regulating peristalsis of the gastrointestinal tract and in functions such as emesis, cognition and anxiety. Therefore, a variety of… (More)
DOI: 10.1016/j.bbrc.2015.09.074