Activation and Evasion of Innate Antiviral Immunity by Herpes Simplex Virus

@inproceedings{Melchjorsen2009ActivationAE,
  title={Activation and Evasion of Innate Antiviral Immunity by Herpes Simplex Virus},
  author={Jesper Melchjorsen and Sampsa Matikainen and S\oren R Paludan},
  booktitle={Viruses},
  year={2009}
}
Herpes simplex virus (HSV), a human pathogenic virus, has evolved several strategies to evade the production and function of interferons (IFNs) and cytokines generated by the innate immune system to restrict the virus. Equilibrium exists between the virus and the immune response, and a shift in this delicate balance either restricts the virus or enhances virus spread and tissue damage. Therefore, understanding of the cytokine response generated after HSV infection and the underlying virus-cell… CONTINUE READING
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