Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy

@article{Li2019ActivatingCP,
  title={Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy},
  author={Anping Li and Ming Yi and Shuang Qin and Yongping Song and Qian Chu and Kongming Wu},
  journal={Journal of Hematology \& Oncology},
  year={2019},
  volume={12}
}
During tumor progression, a subset of cancer cells escape from immune surveillance and eventually develop into measurable tumor mass. Cancer immunotherapy eradicates tumor cells by enhancing multiple steps in cancer-immunity cycle including antigen presentation, T cell priming, activation, and immune killing activity. Immunotherapy has been verified as an effective strategy in multiple cancers, but some problems still exist in actual clinical practice such as frequent primary and adaptive… 
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131 Citations

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