Activated surfaces for laser desorption mass spectrometry: application for peptide and protein analysis.

  title={Activated surfaces for laser desorption mass spectrometry: application for peptide and protein analysis.},
  author={Carlos Afonso and Natali Budimir and Françoise Fournier and Jean-Claude Tabet},
  journal={Current pharmaceutical design},
  volume={11 20},
Thanks to the development of matrix assisted laser desorption/ionisation (MALDI), laser desorption based mass spectrometry became an essential method for the analysis of biomolecules. This review will discuss the various surface modifications used in combination with laser desorption mass spectrometry and their application for the analysis of peptides and proteins. In the first hand, some modified surfaces are designed to enhance the laser desorption/ionisation process; this includes the use of… 
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