Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium.


Confluent cultures of endothelial cells from human umbilical cord were used to study the effect of activated human protein C (APC) on the production of plasminogen activators, plasminogen activator-inhibitor, and factor VIII-related antigen. Addition of APC to the cells in a serum-free medium did not affect the production of tissue-type plasminogen… (More)


8 Figures and Tables