Activated polymorphonuclear leukocytes affect red blood cell aggregability.

@article{Baskurt1998ActivatedPL,
  title={Activated polymorphonuclear leukocytes affect red blood cell aggregability.},
  author={Oguz K. Baskurt and Herbert J. Meiselman},
  journal={Journal of leukocyte biology},
  year={1998},
  volume={63 1},
  pages={
          89-93
        }
}
Activated leukocytes can affect adjacent cells by generating oxygen free radicals and secreting proteolytic enzymes, and red blood cells (RBC) exposed to such agents should be susceptible to their effects. This study was thus designed to investigate the effects of activated polymorphonuclear leukocytes (PMN) on RBC aggregability (i.e., on intrinsic RBC aggregation characteristics). PMN were isolated from human blood by density separation and suspended in glucose-enriched buffer with RBC… CONTINUE READING

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