Activated omentum becomes rich in factors that promote healing and tissue regeneration

  title={Activated omentum becomes rich in factors that promote healing and tissue regeneration},
  author={Natalia O. Litbarg and Krishnamurthy P. Gudehithlu and Perianna Sethupathi and Jose A. L. Arruda and George Dunea and Ashok Kumar Singh},
  journal={Cell and Tissue Research},
In order to study the mechanism by which an omental pedicle promotes healing when applied to an injured site, we injected a foreign body into the abdominal cavity to activate the omentum. One week after the injection, we isolated the omentum and measured blood vessel density, blood content, growth and angiogenesis factors (VEGF and others), chemotactic factors (SDF-1α), and progenitor cells (CXCR-4, WT-1). We found that the native omentum, which consisted mostly of adipose tissue, expanded the… CONTINUE READING
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