Activated microglia contribute to neuronal apoptosis in Toxoplasmic encephalitis

@inproceedings{Zhang2014ActivatedMC,
  title={Activated microglia contribute to neuronal apoptosis in Toxoplasmic encephalitis},
  author={Yi-hua Zhang and He Chen and Ying Chen and Lu Wang and Yi-hong Cai and Min Li and Hui-qin Wen and Jian Du and Ran An and Qing-li Luo and Xue-long Wang and Zhao-rong Lun and Yuan-hong Xu and Ji-long Shen},
  booktitle={Parasites & Vectors},
  year={2014}
}
BackgroundA plethora of evidence shows that activated microglia play a critical role in the pathogenesis of the central nervous system (CNS). Toxoplasmic encephalitis (TE) frequently occurs in HIV/AIDS patients. However, knowledge remains limited on the contributions of activated microglia to the pathogenesis of TE.MethodsA murine model of reactivated encephalitis was generated in a latent infection with Toxoplasma gondii induced by cyclophosphamide. The neuronal apoptosis in the CNS and the… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 12 CITATIONS

Encephalitis is mediated by ROP18 of Toxoplasma gondii, a severe pathogen in AIDS patients.

Ran An, Yuewen Tang, +11 authors Jian Du
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2018
VIEW 2 EXCERPTS
CITES METHODS & BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 44 REFERENCES