Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity.

@article{Mirandola2004ActivatedHN,
  title={Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity.},
  author={Prisco Mirandola and Cristina Ponti and Giuliana Gobbi and Ivonne Sponzilli and Mauro Vaccarezza and Lucio Cocco and Giorgio Zauli and Paola Secchiero and Francesco Antonio Manzoli and Marco Vitale},
  journal={Blood},
  year={2004},
  volume={104 8},
  pages={2418-24}
}
The expression of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors was investigated in resting and cytokine-activated purified primary human natural killer (NK) and CD8(+) T cells. Resting NK and CD8(+) T cells expressed the mRNA for all TRAIL receptors, but TRAIL-R4 was the only receptor clearly detectable on the… CONTINUE READING