Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms.


PURPOSE This consistent observation of a reduction of the elastin concentration in abdominal aortic aneurysms (AAAs) has led us to investigate in AAA specimens two metalloproteinases that display elastase activity, MMP2 (gelatinase A/72kDa) and MMP9 (gelatinase B/92 kDa). METHODS Samples of full-thickness aortic wall, adherent thrombus, and serum were… (More)


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