Corpus ID: 40270796

Activated T cells acquire endothelial cell surface determinants during transendothelial migration.

@article{Brezinschek1999ActivatedTC,
  title={Activated T cells acquire endothelial cell surface determinants during transendothelial migration.},
  author={R. Brezinschek and N. Oppenheimer-Marks and P. Lipsky},
  journal={Journal of immunology},
  year={1999},
  volume={162 3},
  pages={
          1677-84
        }
}
Activated T cells acquire endothelial cell (EC) plasma membrane constituents during transendothelial migration. This was assessed using an in vitro model system in which human peripheral blood CD4+ T cells migrated through confluent monolayers of HUVEC. Flow cytometry of migrated CD4+ T cells demonstrated that activated, but not resting, T cells acquired a variety of endothelial surface determinants, including CD31, CD49d, CD54, CD61, and CD62E. The extracellular domains of these molecules were… Expand
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