Activated Phosphorylated STAT1 Levels as a Biologically Relevant Immune Signal in Schizophrenia.

Abstract

OBJECTIVE Activation of STAT1 is directly downstream of the cytokine receptors that signal from specific proinflammatory cytokines known to be dysregulated in schizophrenia (SZ), such as IFNγ, IL6, IL2 and IL10, as well as hypoxia, viral/bacterial infections and peptide growth factors. If the increased cytokine protein levels repeatedly observed in SZ have… (More)
DOI: 10.1159/000450581

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