Activated Antigen-Specific CD8+ T Cells Persist in the Lungs Following Recovery from Respiratory Virus Infections1

@article{Hogan2001ActivatedAC,
  title={Activated Antigen-Specific CD8+ T Cells Persist in the Lungs Following Recovery from Respiratory Virus Infections1},
  author={R. Hogan and E. Usherwood and W. Zhong and Alan D. Roberts and R. Dutton and A. Harmsen and D. Woodland},
  journal={The Journal of Immunology},
  year={2001},
  volume={166},
  pages={1813 - 1822}
}
The poor correlation between cellular immunity to respiratory virus infections and the numbers of memory CD8+ T cells in the secondary lymphoid organs suggests that there may be additional reservoirs of T cell memory to this class of infection. Here we identify a substantial population of Ag-specific T cells in the lung that persist for several months after recovery from an influenza or Sendai virus infection. These cells are present in high numbers in both the airways and lung parenchyma and… Expand
Nonspecific Recruitment of Memory CD8+ T Cells to the Lung Airways During Respiratory Virus Infections1
Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung
Cutting Edge: Virus-Specific CD4+ Memory T Cells in Nonlymphoid Tissues Express a Highly Activated Phenotype1
Long‐term persistence and reactivation of T cell memory in the lung of mice infected with respiratory syncytial virus
  • Tobias Ostler, Tracy Hussell, Charles D. Surh, Peter Openshaw, S. Ehl
  • Biology, Medicine
  • European journal of immunology
  • 2001
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References

SHOWING 1-10 OF 69 REFERENCES
Functionally Heterogeneous CD8+ T-Cell Memory Is Induced by Sendai Virus Infection of Mice
  • Edward J. Usherwood, R. Hogan, +4 authors David L. Woodland
  • Biology, Medicine
  • Journal of Virology
  • 1999
Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.
Virus-specific CD8+ T cells in primary and secondary influenza pneumonia.
In vivo proliferation of naïve and memory influenza-specific CD8(+) T cells.
Functionally distinct T cells in three compartments of the respiratory tract after influenza virus infection
  • Nicole Baumgarth, A. Kelso
  • Biology, Medicine
  • European journal of immunology
  • 1996
Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells.
CD4+ T Cell Priming Accelerates the Clearance of Sendai Virus in Mice, but Has a Negative Effect on CD8+ T Cell Memory1
  • Weimin Zhong, D. Marshall, Christopher Coleclough, David L. Woodland
  • Biology, Medicine
  • The Journal of Immunology
  • 2000
On the role of antigen in maintaining cytotoxic T-cell memory.
Long-Term Persistence of Activated Cytotoxic T Lymphocytes after Viral Infection of the Central Nervous System
...
1
2
3
4
5
...