Activated Akt expression has significant correlation with EGFR and TGF-alpha expressions in stage I NSCLC.

@article{Mukohara2004ActivatedAE,
  title={Activated Akt expression has significant correlation with EGFR and TGF-alpha expressions in stage I NSCLC.},
  author={Toru Mukohara and Shinzoh Kudoh and Kuniomi Matsuura and Setsuko Yamauchi and Tatsuo Kimura and Naruo Yoshimura and Hiroshi Kanazawa and Kazuto Hirata and Kiyotoshi Inoue and Hideki Wanibuchi and Shoji Fukushima and Junichi Yoshikawa},
  journal={Anticancer research},
  year={2004},
  volume={24 1},
  pages={11-7}
}
BACKGROUND In vitro studies have indicated that epidermal growth factor receptor (EGFR) may intensify signaling output by the receptor's overexpression, heterodimerization with HER-2, or autocrine expression of ligands. The purpose of the present study was to evaluate the correlation between EGFR and its related proteins and to explore the prognostic value of the proteins. MATERIALS AND METHODS Immunohistochemical staining of transforming growth factor alpha (TGF-alpha), EGFR, HER-2, and… CONTINUE READING
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