Activated Akt Protects the Lung from Oxidant-Induced Injury and Delays Death of Mice

@article{Lu2001ActivatedAP,
  title={Activated Akt Protects the Lung from Oxidant-Induced Injury and Delays Death of Mice},
  author={Yunbiao Lu and Lisa Parkyn and Leo E Otterbein and Yasuko Kureishi and Kenneth Walsh and Anuradha Ray and Prabir Ray},
  journal={The Journal of Experimental Medicine},
  year={2001},
  volume={193},
  pages={545 - 550}
}
Oxidant-induced injury to the lung causes extensive damage to lung epithelial cells. Impaired protection and repair of the lung epithelium can result in death. The serine-threonine kinase Akt has been implicated in inhibiting cell death induced by different stimuli including growth factor withdrawal, cell cycle discordance, DNA damage, and loss of cell… CONTINUE READING