Actions of reactive oxygen species on AH/type 2 myenteric neurons in guinea pig distal colon.

@article{WadaTakahashi2000ActionsOR,
  title={Actions of reactive oxygen species on AH/type 2 myenteric neurons in guinea pig distal colon.},
  author={Satoko Wada-Takahashi and Kenji Tamura},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2000},
  volume={279 5},
  pages={G893-902}
}
With conventional intracellular recording methods, we investigated the mechanism of actions of reactive oxygen species (ROS) derived from hypoxanthine and xanthine oxidase (HX/XO) reactions on AH/type 2 myenteric neurons in the guinea pig distal colon. Of the 54 neurons to which HX/XO was applied, 32 neurons showed a transient membrane hyperpolarization(s) followed by a long-lasting membrane depolarization. Two additional groups of 10 myenteric neurons exhibited only a membrane… CONTINUE READING

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