Actions of melatonin in the reduction of oxidative stress. A review.

  title={Actions of melatonin in the reduction of oxidative stress. A review.},
  author={Russell J Reiter and Denise Tan and Carmen Osuna and Eloisa Gitto},
  journal={Journal of biomedical science},
  volume={7 6},
Melatonin was discovered to be a direct free radical scavenger less than 10 years ago. Besides its ability to directly neutralize a number of free radicals and reactive oxygen and nitrogen species, it stimulates several antioxidative enzymes which increase its efficiency as an antioxidant. In terms of direct free radical scavenging, melatonin interacts with the highly toxic hydroxyl radical with a rate constant equivalent to that of other highly efficient hydroxyl radical scavengers… CONTINUE READING
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Nitrosa - tion of melatonin by nitric oxide and peroxyni - trite

  • B Blanchard, D Pompom, C Ducrocq
  • J Pineal Res
  • 2000

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