Actions of dietary orotic acid on liver synthesis of phosphatidylcholine and phosphatidylethanolamine in rats.

@article{Haines1987ActionsOD,
  title={Actions of dietary orotic acid on liver synthesis of phosphatidylcholine and phosphatidylethanolamine in rats.},
  author={D. Haines and S. Tokmakjian},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={1987},
  volume={65 2},
  pages={
          105-11
        }
}
  • D. Haines, S. Tokmakjian
  • Published 1987
  • Medicine
  • Biochemistry and cell biology = Biochimie et biologie cellulaire
The in vivo rates of the reactions of the cytidine pathways of liver phosphatidylcholine and phosphatidylethanolamine synthesis were measured in rats after 1 day of feeding on a semisynthetic diet containing 1% orotic acid. The calculations were made from the specific and total radioactivity versus time curves of the precursors and products following intraportal injection of [1,2-14C]choline, [2-14C]ethanolamine, and [2-3H]glycerol. The liver CTP level was increased twofold and the rates of CDP… Expand
2 Citations
Dietary orotic acid accentuates the hepatic response to phenobarbital in rats.