Actions of cAMP on calcium sensitization in human detrusor smooth muscle contraction.

@article{Hayashi2016ActionsOC,
  title={Actions of cAMP on calcium sensitization in human detrusor smooth muscle contraction.},
  author={Maya Hayashi and Shunichi Kajioka and Momoe Itsumi and Ryosuke Takahashi and Nouval Shahab and Takao Ishigami and Masahiro Takeda and N. Masuda and Akito Yamaguchi and Seiji Naito},
  journal={BJU international},
  year={2016},
  volume={117 1},
  pages={179-91}
}
OBJECTIVES To clarify the effect of cAMP on the Ca(2+) -sensitized smooth muscle contraction in human detrusor, as well as the role of novel exchange protein directly activated by cAMP (Epac) in cAMP-mediated relaxation. MATERIALS AND METHODS All experimental protocols to record isometric tension force were performed using α-toxin-permeabilized human… CONTINUE READING