Actions of adenosine A 2A receptors on synaptic connections of spiny projection neurons in the neostriatal inhibitory network.

Abstract

There is growing evidence that adenosine plays a crucial role in basal ganglia function, particularly in the modulation of voluntary movement. An adenosine-based treatment for Parkinson's disease shows promise in recent clinical studies. Adenosine A(2A) receptors, the receptors involved in this treatment, are highly expressed in the neostriatum. Previous… (More)
DOI: 10.1152/jn.01259.2007

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@article{Shindou2008ActionsOA, title={Actions of adenosine A 2A receptors on synaptic connections of spiny projection neurons in the neostriatal inhibitory network.}, author={Tomomi Shindou and Gordon W. Arbuthnott and Jeffery R. Wickens}, journal={Journal of neurophysiology}, year={2008}, volume={99 4}, pages={1884-9} }