Actions and interactions of extracellular potassium and kainate on expression of 13 gamma-aminobutyric acid type A receptor subunits in cultured mouse cerebellar granule neurons.

@article{Engblom2003ActionsAI,
  title={Actions and interactions of extracellular potassium and kainate on expression of 13 gamma-aminobutyric acid type A receptor subunits in cultured mouse cerebellar granule neurons.},
  author={A Christine Engblom and Flemming Fryd Johansen and Uffe Kristiansen},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 19},
  pages={16543-50}
}
Cerebellar granule neurons in culture are a popular model for studying neuronal signaling and development. Depolarizing concentrations of K(+) are routinely used to enhance cell survival, and kainate is sometimes added to eliminate GABAergic neurons. We have investigated the effect of these measures on expression of mRNA for gamma-aminobutyric acid type A… CONTINUE READING