Actions and interactions of benzodiazepine agonists, antagonists and inverse agonists on suprahyoid muscle twitching.

@article{James1985ActionsAI,
  title={Actions and interactions of benzodiazepine agonists, antagonists and inverse agonists on suprahyoid muscle twitching.},
  author={V. James and C. Gardner},
  journal={European journal of pharmacology},
  year={1985},
  volume={113 2},
  pages={
          233-8
        }
}
Amphetamine-induced twitching of the suprahyoid muscle in nialamide-pretreated, urethane-anaesthetised rats was inhibited by the benzodiazepine agonists RU 32007, diazepam and chlordiazepoxide and the GABAA agonist muscimol. Ro15-1788 and CGS 8216 induced slight, or no reduction in twitching, respectively, but reversed the effect of RU 32007 and diazepam. Ro15-1788 did not reverse the effect of muscimol. Picrotoxin reversed both muscimol and RU 32007 effects at a dose which induced only a small… Expand
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