Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor.

@article{Brainard2001ActionSF,
  title={Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor.},
  author={G C Brainard and John P. Hanifin and Jeffrey M. Greeson and B Byrne and G Glickman and E Gerner and Mark D. Rollag},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2001},
  volume={21 16},
  pages={6405-12}
}
The photopigment in the human eye that transduces light for circadian and neuroendocrine regulation, is unknown. The aim of this study was to establish an action spectrum for light-induced melatonin suppression that could help elucidate the ocular photoreceptor system for regulating the human pineal gland. Subjects (37 females, 35 males, mean age of 24.5 +/- 0.3 years) were healthy and had normal color vision. Full-field, monochromatic light exposures took place between 2:00 and 3:30 A.M. while… CONTINUE READING
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